Anti-TPMT Polyclonal Antibody
产品名称: Anti-TPMT Polyclonal Antibody
英文名称: Anti-TPMT Polyclonal Antibody
产品编号: K001870P
产品价格: null
产品产地: 北京
品牌商标: Solarbio
更新时间: 2025-11-06T11:14:17
使用范围:
北京索莱宝科技有限公司
- 联系人 : 索莱宝-龚思雨
- 地址 : 北京市北京经济技术开发区环科中路16号26幢3层301
- 邮编 :
- 所在区域 : 北京
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- 邮箱 : 3193328036@qq.com
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Anti-TPMT Polyclonal Antibody
Anti-TPMT Polyclonal Antibody
品牌:solarbio | 货号:K001870P
| 英文名称 | Anti-TPMT Polyclonal Antibody |
|---|---|
| 别名 | TPMTD |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:10-100. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 28kDa |
| Gene ID | 7172 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human TPMT |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human TPMT |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P51580 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals, causing thiopurine S-methyltransferase deficiency. Related pseudogenes have been identified on chromosomes 3, 18 and X. |
