Anti-CTNNB1 Polyclonal Antibody
产品名称： Anti-CTNNB1 Polyclonal Antibody
英文名称： Anti-CTNNB1 Polyclonal Antibody
产品编号： K002270P
产品价格： null
产品产地： 北京
品牌商标： solarbio
更新时间： 2025-11-06T11:17:45
使用范围： WB IHC IP
北京索莱宝科技有限公司
- 联系人 : 索莱宝-龚思雨
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Anti-CTNNB1 Polyclonal Antibody
品牌：solarbio | 货号：K002270P
| 英文名称 | Anti-CTNNB1 Polyclonal Antibody |
|---|---|
| 别名 | CTNNB;MRD19;armadillo |
| 应用 | WB IHC IP |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IP 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 85kDa |
| Gene ID | 1499 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human CTNNB1 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human CTNNB1 |
| Subcellular Locations | Cell junction Cell membrane Cytoplasm Nucleus adherens junction centrosome cytoskeleton microtubule organizing center spindle pole |
| Swiss Prot | P35222 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. |