Anti-CDK4 Monoclonal Antibody

商品货号：	商品品牌：	规格	基本售价：	选择规格
K000051M-50ul	Solarbio	50ul	960.00元
K000051M-100ul	Solarbio	100ul	1600.00元

英文名称	Mouse CDK4 Monoclonal Antibody
应用2	WB
克隆类型2	Monoclonal Antibody
别名	CDK4
应用	WB
稀释比例	WB1:1000 ICC
交叉反应	Human Mouse Rat
蛋白分子量	33kDa
Gene ID	1019
保存	Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment.
储存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 60% Glycerol.
纯化方法	Affinity purification
亚型	IgG1
免疫原	Purified recombinant human CDK4 protein fragments expressed in E.coli.
性状	Lyophilized or Liquid
Swiss Prot	P11802
克隆号	3F9-B12-C8
克隆类型	Monoclonal Antibody
来源	Mouse
背景资料	The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported.